A New Era of Evidence-Based Care

For years, women have faced fear and confusion around hormone therapy. But now, there’s good news. The FDA recently announced the removal of outdated “black box” warnings from menopausal hormone therapy products — a major shift that reflects what modern research has shown all along: when prescribed appropriately and started at the right time, hormone therapy is both safe and highly beneficial.

At True Precision Medicine in Pittsburgh, we welcome this change. It aligns with what we’ve always believed — that hormone therapy should be personalized, evidence-based, and focused on restoring balance to help women feel their best at every stage of life.

What the New FDA Guidance Means for Women

The FDA’s updated recommendations are based on decades of newer, high-quality research. Here’s what’s changed:

  • Black box warnings removed: Older studies suggested high risks of heart disease, dementia, and breast cancer. New evidence shows those risks are very low when treatment starts at the right time.

  • Best time to begin: Hormone therapy is now recommended to start within 10 years of menopause onset or before age 60 for systemic treatments.

  • Focus on individualized care: The FDA now encourages a more nuanced, personalized approach — not one-size-fits-all warnings.

This shift helps reduce unnecessary fear and highlights what many women have already experienced firsthand: when hormone therapy is tailored to your body, it can improve your quality of life in meaningful, lasting ways.

Understanding Hormone Imbalance

Hormones regulate nearly every major system in your body — from mood and sleep to metabolism and sexual health. When even one hormone falls out of balance, the effects can be widespread.

Common symptoms of hormone imbalance in women include:

  • Hot flashes and night sweats

  • Fatigue or low energy

  • Weight gain or excess belly fat

  • Anxiety, depression, or mood swings

  • Brain fog or memory problems

  • Low libido

  • Vaginal dryness or discomfort

And for many women, these symptoms can appear well before menopause — during perimenopause or even earlier due to stress, thyroid disorders, or other underlying conditions.

Our Approach: Bioidentical Hormone Therapy

At True Precision Medicine, we use bioidentical hormone replacement therapy (BHRT) to restore your hormones to optimal levels naturally and safely.

Bioidentical hormones are derived from plant sources and are molecularly identical to the hormones your body produces. This makes them easier for your body to use — and helps minimize side effects compared to synthetic alternatives.

Your care begins with a comprehensive lab profile and health assessment, followed by a custom treatment plan designed specifically for your needs. We partner with you every step of the way to rebalance your hormones and help you feel like yourself again.

Benefits of Hormone Optimization

When started within the FDA’s recommended window and carefully managed, hormone therapy has been shown to provide a range of benefits:

  • Relief from hot flashes, night sweats, and mood swings

  • Better sleep and energy

  • Improved focus and mental clarity

  • Reduced risk of osteoporosis and fractures

  • Healthier cardiovascular function

  • Support for libido and sexual health

These benefits reflect the latest understanding of how hormone therapy — when personalized — can enhance long-term health and vitality.

Personalized. Evidence-Based. For You.

At True Precision Medicine, we believe in treating the root cause of hormone imbalance, not just the symptoms. Our precision approach means your therapy is based on your unique lab data, your goals, and your body’s natural rhythm.

With the FDA’s new guidance supporting individualized, science-based care, there’s never been a better time to explore your options.

Ready to restore balance and feel your best again?
Schedule your personalized hormone consultation today.

True Precision Medicine – Pittsburgh, PA
(412) 920-4100

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